Publications.

2021

 

​2020

  • Evans PC, Fragiadaki M, Morris PD & Serbanovic-Canic J (2020) Shear stress : the dark energy of atherosclerotic plaques. Cardiovascular Research. 

  • Ward AO, Angelini GD, Caputo M, Evans PC, Johnson JL, Suleiman MS, Tulloh RM, George SJ & Zakkar M (2020) NF-κB inhibition prevents acute shear stress-induced inflammation in the saphenous vein graft endothelium. Scientific Reports, 10(1).  

  • Pirri D, Fragiadaki M & Evans PC (2020) Diabetic atherosclerosis: is there a role for the hypoxia-inducible factors?. Bioscience Reports, 40(8).  

  • Morris PD, Gosling R, Zwierzak I, Evans H, Aubiniere-Robb L, Czechowicz K, Evans PC, Hose DR, Lawford PV, Narracott A & Gunn JP (2020) A novel method for measuring absolute coronary blood flow & microvascular resistance in patients with ischaemic heart disease. Cardiovascular Research.   

  • Naase H, Harling L, Kidher E, Sepehripour A, Nguyen B, Kapelouzou A, Cokkinos D, Stavridis G, Angelini G, Evans PC & Athanasiou T (2020) Toll-like receptor 9 and the inflammatory response to surgical trauma and cardiopulmonary bypass. Journal of Cardiothoracic Surgery, 15.  

  • Alexander Y, Osto E, Schmidt-Trucksäss A, Shechter M, Trifunovic D, Duncker DJ, Aboyans V, Bäck M, Badimon L, Cosentino F , De Carlo M et al (2020) Endothelial function in cardiovascular precision medicine: A position paper on behalf of the European Society of Cardiology. Cardiovascular Research.   

  • Mahmoud MM, Serbanovic-Canic J, Feng S, Souilhol C, Xing R, Hsiao S, Mammoto A, Chen J, Ariaans M, Francis SE , Van der Heiden K et al (2020) Author Correction: Shear stress induces endothelial-to-mesenchymal transition via the transcription factor Snail. Scientific Reports, 10(1).  

  • Gomez I, Ward B, Souilhol C, Recarti C, Ariaans M, Johnston J, Burnett A, Mahmoud M, Luong LA, West L , Long M et al (2020) Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium. Nature Communications, 11(1).   

  • Souilhol C, Serbanovic-Canic J, Fragiadaki M, Chico TJ, Ridger V, Roddie H & Evans PC (2020) Endothelial responses to shear stress in atherosclerosis: a novel role for developmental genes. Nature Reviews Cardiology, 17(1), 52-63.

2019 

  • Gijsen F, Katagiri Y, Barlis P, Bourantas C, Collet C, Coskun U, Daemen J, Dijkstra J, Edelman E, Evans P , van der Heiden K et al (2019) Expert recommendations on the assessment of wall shear stress in human coronary arteries : existing methodologies, technical considerations, and clinical applications. European Heart Journal, 40(41), 3421-3433.   

  • Souilhol C, Gauci I, Feng S, Tardajos Ayllon B, Mahmoud M, Canham L, Fragiadaki M, Serbanovic-Canic J, Ridger V & Evans PC (2019) Homeobox B9 integrates bone morphogenic protein 4 with inflammation at atheroprone sites. Cardiovascular Research. 

  • Ketelhuth DFJ, Lutgens E, Bäck M, Binder CJ, Van den Bossche J, Daniel C, Dumitriu IE, Hoefer I, Libby P, O’Neill L , Weber C et al (2019) Immunometabolism and atherosclerosis: perspectives and clinical significance: a position paper from the Working Group on Atherosclerosis and Vascular Biology of the European Society of Cardiology. Cardiovascular Research, 115(9), 1385-1392.  

  • Xanthis I, Souilhol C, Serbanovic-Canic J, Roddie H, Kalli AC, Fragiadaki M, Wong R, Shah DR, Askari JA, Canham L , Akhtar N et al (2019) β1 integrin is a sensor of blood flow direction. Journal of Cell Science.   

  • Ayllón BT, Souilhol C, Oakley F & Evans P (2019) BS14 c-Rel drives atherosclerosis at sites of disturbed blood flow by activating inflammatory and proliferative transcriptional programmes in endothelium. Heart, 105(Suppl 6), a148.  

  • Roddie H, Fragiadaki M & Evans P (2019) BS28 Endothelial STAT5A is enriched at atheroprone regions of the aorta and drives inflammation in response to low shear stress. Heart, 105(Suppl 6), a158.  

  • Souilhol C, Canham L, Xueqi J & Evans P (2019) BS3 Notch ligand JAG1 promotes endothelial-to-mesenchymal transition and atherosclerosis at regions of disturbed flow. Heart, 105(Suppl 6), a142.  

  • Serbanovic-Canic J, Souilhol C & Evans PC (2019) Shear stress makes its mark on the endothelial genome.. Cardiovascular Research.   

  • Baeriswyl DC, Prionisti I, Peach T, Tsolkas G, Chooi KY, Vardakis J, Morel S, Diagbouga MR, Bijlenga P, Cuhlmann S , Evans P et al (2019) Disturbed flow induces a sustained, stochastic NF-κB activation which may support intracranial aneurysm growth in vivo. Scientific Reports, 9(1).   

  • Mahmoud M, Souilhol C, Serbanovic-Canic J & Evans P (2019) GATA4-Twist1 Signalling in Disturbed Flow-Induced Atherosclerosis. Cardiovascular Drugs and Therapy.  

  • Tuñón J, Badimón L, Bochaton-Piallat M-L, Cariou B, Daemen MJ, Egido J, Evans PC, Hoefer IE, Ketelhuth DFJ, Lutgens E , Matter CM et al (2019) Identifying the anti-inflammatory response to lipid lowering therapy: a position paper from the working group on atherosclerosis and vascular biology of the European Society of Cardiology. Cardiovascular Research, 115(1), 10-19. 

2018

  • Fragiadaki M & Evans PC (2018) The Bernard and Joan Marshall Early Career Investigators and Distinguished Investigator Award 2018. Cardiovascular Drugs and Therapy.   

  • Xing R, Moerman AM, Ridwan RY, van Gaalen K, Meester EJ, van der Steen AFW, Evans PC, Gijsen FJH & Van der Heiden K (2018) The effect of the heart rate lowering drug Ivabradine on hemodynamics in atherosclerotic mice. Scientific Reports, 8(1). 

  • Caporali A, Bäck M, Daemen MJ, Hoefer IE, Jones EA, Lutgens E, Matter CM, Bochaton-Piallat M-L, Siekmann AF, Sluimer JC , Steffens S et al (2018) Future directions for therapeutic strategies in post-ischaemic vascularization: a position paper from European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology.. Cardiovascular Research, 114(11), 1411-1421. 

  • Alfaidi MA, Chamberlain J, Rothman A, Crossman D, Villa‐Uriol MC, Hadoke P, Wu J, Schenkel T, Evans PC & Francis SE (2018) Dietary Docosahexaenoic Acid Reduces Oscillatory Wall Shear Stress, Atherosclerosis, and Hypertension, Most Likely Mediated via an IL‐1–Mediated Mechanism. Journal of the American Heart Association, 7(13). 

  • Tuñón J, Bäck M, Badimón L, Bochaton-Piallat M-L, Cariou B, Daemen MJ, Egido J, Evans PC, Francis SE, Ketelhuth DFJ , Lutgens E et al (2018) Interplay between hypercholesterolaemia and inflammation in atherosclerosis: Translating experimental targets into clinical practice. European Journal of Preventive Cardiology, 25(9), 948-955.  

  • Evans PC, Gijsen FJH, Wentzel JJ & van der Heiden K (2018) Biomechanics in vascular biology and cardiovascular disease. Thrombosis and Haemostasis, 115(3), 465-466.  

  • Green J, Souilhiol C, Xanthis I, Martinez-Campesino L, Bowden N, Evans P & Wilson H (2018) Atheroprone flow activates inflammation via endothelial ATP-dependent P2X7-p38 signalling. Cardiovascular Research, 114(2), 324-335. 

 

  2017

  • Luong L, Duckles H, Schenkel T, Mahmoud M, Lopez-Tremoleda JL, Wylezinska-Arridge M, Ali M, Bowden NP, Villa-Uriol M, van der Heiden K , Xing R et al (2017) Heart rate reduction with ivabradine promotes shear stress-dependent anti-inflammatory mechanisms in arteries. Thrombosis and Haemostasis, 116(1), 181-190.  

  • Feng S, Bowden N, Fragiadaki M, Souilhol C, Hsiao S, Mahmoud M, Allen S, Pirri D, Ayllon BT, Akhtar S , Thompson AAR et al (2017) Mechanical Activation of Hypoxia-Inducible Factor 1α Drives Endothelial Dysfunction at Atheroprone Sites.. Arteriosclerosis, Thrombosis, and Vascular Biology, 37(11), 2087-2101. 

  • Mahmoud M, Serbanovic-Canic J, Feng S, Souilhol C, Xing R, Hsiao S, Mammoto A, Chen J, Ariaans M, Francis S , Van der Heiden K et al (2017) Shear stress induces endothelial-to-mesenchymal transition via the transcription factor Snail. Scientific Reports, 7. 

  • Ridger VC, Boulanger CM, Angelillo-Scherrer A, Badimon L, Blanc-Brude O, Bochaton-Piallat M-L, Boilard E, Buzas EI, Caporali A, Dignat-George F , Evans PC et al (2017) Microvesicles in vascular homeostasis and diseases. Position Paper of the European Society of Cardiology (ESC) Working Group on Atherosclerosis and Vascular Biology.. Thromb Haemost, 117(7), 1296-1316. 

2016

  • Hsiao ST, Spencer T, Boldock L, Prosseda SD, Xanthis I, Tovar-Lopez FJ, Van Beusekom HMM, Khamis RY, Foin N, Bowden N , Hussain A et al (2016) Endothelial repair in stented arteries is accelerated by inhibition of Rho-associated protein kinase. Cardiovascular Research, 112(3), 689-701. View this article in WRRO  

  • Serbanovic-Canic J, de Luca A, Warboys C, Ferreira PF, Luong LA, Hsiao S, Gauci I, Mahmoud M, Feng S, Souilhol C , Bowden N et al (2016) Zebrafish Model for Functional Screening of Flow-Responsive Genes.. Arterioscler Thromb Vasc Biol, 37, 130-143. View this article in WRRO  

  • Bowden N, Bryan MT, Duckles H, Feng S, Hsiao S, Kim HR, Mahmoud M, Moers B, Serbanovic-Canic J, Xanthis I , Ridger VC et al (2016) Experimental Approaches to Study Endothelial Responses to Shear Stress. Antioxidants & Redox Signaling, 25(7), 389-400.  

  • Halliday I, Lishchuk SV, Spencer TJ, Pontrelli G & Evans PC (2016) Local membrane length conservation in two-dimensional vesicle simulation using a multicomponent lattice Boltzmann equation method. Physical Review E, 94(2).  

  • Mahmoud M, Kim HR, Xing R, Hsiao S, Mammmoto A, Chen J, Serbanovic-Canic J, Feng S, Bowden NP, Maguire R , Ariaans M et al (2016) TWIST1 Integrates Endothelial Responses to Flow in Vascular Dysfunction and Atherosclerosis. Circulation Research, 119, 450-462. View this article in WRRO  

  • Holloway PM, Gillespie S, Becker F, Vital SA, Nguyen V, Alexander JS, Evans PC & Gavins FNE (2016) Sulforaphane induces neurovascular protection against a systemic inflammatory challenge via both Nrf2-dependent and independent pathways. Vascular Pharmacology, 85, 29-38.  

  • Nguyen BAV, Fiorentino F, Reeves BC, Baig K, Athanasiou T, Anderson JR, Haskard DO, Angelini GD & Evans PC (2016) Mini Bypass and Proinflammatory Leukocyte Activation: A Randomized Controlled Trial. The Annals of Thoracic Surgery, 101(4), 1454-1463.  

  • Brown AJ, Teng Z, Evans PC, Gillard JH, Samady H & Bennett MR (2016) Role of biomechanical forces in the natural history of coronary atherosclerosis. Nature Reviews Cardiology, 13(4), 210-220.  

  • Morris PD, Narracott A, Von Tengg-Kobligk H, Soto DAS, Hsiao S, Lungu A, Evans P, Bressloff NW, Lawford PV, Rodney Hose D & Gunn JP (2016) Computational fluid dynamics modelling in cardiovascular medicine. Heart, 102(1), 18-28. View this article in WRRO

2015  

  • Hoefer IE, Steffens S, Ala-Korpela M, Bäck M, Badimon L, Bochaton-Piallat M-L, Boulanger CM, Caligiuri G, Dimmeler S, Egido J , Evans PC et al (2015) Novel methodologies for biomarker discovery in atherosclerosis. European Heart Journal, 36(39), 2635-2642.  

  • Mylroie H, Dumont O, Bauer A, Thornton CC, Mackey J, Calay D, Hamdulay SS, Choo JR, Boyle JJ, Samarel AM , Randi AM et al (2015) PKC -CREB-Nrf2 signalling induces HO-1 in the vascular endothelium and enhances resistance to inflammation and apoptosis. Cardiovascular Research, 106(3), 509-519. View this article in WRRO  

  • Kidher E, Jarral OA, Harling L, Anderson JR, Chukwuemeka A, Ashrafian H, Evans PC & Athanasiou T (2015) NR2 antibody is associated with quality of life in aortic valve replacement. Asian Cardiovascular and Thoracic Annals, 23(6), 690-700.  

  • Di Marco LY, Venneri A, Farkas E, Evans PC, Marzo A & Frangi AF (2015) Vascular dysfunction in the pathogenesis of Alzheimer's disease — A review of endothelium-mediated mechanisms and ensuing vicious circles. Neurobiology of Disease, 82, 593-606. View this article in WRRO  

  • Enesa K, Moll HP, Luong L, Ferran C & Evans PC (2015) A20 suppresses vascular inflammation by recruiting proinflammatory signaling molecules to intracellular aggresomes. The FASEB Journal, 29(5), 1869-1878. View this article in WRRO

2014  

  • Li J, Hou B, Tumova S, Muraki K, Bruns A, Ludlow MJ, Sedo A, Hyman AJ, McKeown L, Young RS , Yuldasheva NY et al (2014) Piezo1 integration of vascular architecture with physiological force. Nature, 515(7526), 279-282. View this article in WRRO  

  • Kidher E, Harling L, Sugden C, Ashrafian H, Casula R, Evans P, Nihoyannopoulos P & Athanasiou T (2014) Aortic stiffness is an indicator of cognitive dysfunction before and after aortic valve replacement for aortic stenosis. Interactive CardioVascular and Thoracic Surgery, 19(4), 595-604.  

  • Kwak BR, Bäck M, Bochaton-Piallat M-L, Caligiuri G, Daemen MJAP, Davies PF, Hoefer IE, Holvoet P, Jo H, Krams R , Lehoux S et al (2014) Biomechanical factors in atherosclerosis: mechanisms and clinical implications. European Heart Journal, 35(43), 3013-3020.  

  • Cuhlmann S, Gsell W, Van der Heiden K, Habib J, Tremoleda JL, Khalil M, Turkheimer F, Meens MJ, Kwak BR, Bird J , Davenport AP et al (2014) In Vivo Mapping of Vascular Inflammation Using the Translocator Protein Tracer 18 F-FEDAA1106. Molecular Imaging, 13(6), 7290.2014.00014-7290.2014.00014.  

  • Mahmoud M, Kim R, De Luca A, Gauci I, Hsiao S & Evans PC (2014) P470Disturbed flow promotes endothelial cell injury via the induction of developmental genes. Cardiovascular Research, 103(suppl 1), S86.1-S86.  

  • Hsiao S, Tovar-Lopez FJ, Gunn J, Spencer T, Halliday I, Perrault C & Evans PC (2014) 292Endothelial cell forward migration in a disturbed wall shear stress environment is promoted by ROCK inhibition. Cardiovascular Research, 103(suppl 1), S53.3-S53.  

  • Bryan MT, Duckles H, Feng S, Hsiao ST, Kim HR, Serbanovic-Canic J & Evans PC (2014) Mechanoresponsive networks controlling vascular inflammation.. Arterioscler Thromb Vasc Biol, 34(10), 2199-2205.  

  • Nguyen BAV, Suleiman M-S, Anderson JR, Evans PC, Fiorentino F, Reeves BC & Angelini GD (2014) Metabolic derangement and cardiac injury early after reperfusion following intermittent cross-clamp fibrillation in patients undergoing coronary artery bypass graft surgery using conventional or miniaturized cardiopulmonary bypass.. Mol Cell Biochem, 395(1-2), 167-175.  

  • Amini N, Boyle JJ, Moers B, Warboys CM, Malik TH, Zakkar M, Francis SE, Mason JC, Haskard DO & Evans PC (2014) Requirement of JNK1 for endothelial cell injury in atherogenesis.. Atherosclerosis, 235(2), 613-618.  

  • Hsiao S, Tovar F, Gunn J, Spencer T, Halliday I, Perrault C & Evans P (2014) 219 Rock Inhibits Endothelial Migration in Disturbed flow Condition: A Potential Therapeutic Target in PCI. Heart, 100(Suppl 3), A120.1-A120.  

  • Gauci I, Luong L, Mahmoud M, Duckles H, Hsiao S, DeLuca A & Evans P (2014) 192 The Induction of Homeobox Genes by Disturbed Flow Limits Inflammation at Atherosusceptible Sites. Heart, 100(Suppl 3), A106.2-A107.  

  • Mahmoud M, Kim R, de Luca A, Gauci I, Hsiao S & Evans P (2014) 189 Disturbed Flow Promotes Endothelial Cell Injury Via the Induction of Developmental Genes. Heart, 100(Suppl 3), A105.2-A105.  

  • Warboys CM, de Luca A, Amini N, Luong L, Duckles H, Hsiao S, White A, Biswas S, Khamis R, Chong CK , Cheung W-M et al (2014) Disturbed flow promotes endothelial senescence via a p53-dependent pathway.. Arterioscler Thromb Vasc Biol, 34(5), 985-995.  

  • Enesa K & Evans P (2014) The Biology of A20-Like Molecules, 33-48.  

  • Nguyen B, Naase H, Jakaj G, Finch J, Boyle J, de Luca A, Haskard DO, Luong L, Evans PC, Vives M , Mulholland JW et al (2014) Sulforaphane pretreatment prevents systemic inflammation and renal injury in response to cardiopulmonary bypass. Journal of Thoracic and Cardiovascular Surgery.

2013  

  • Wells RE, Barry JD, Warrington SJ, Cuhlmann S, Evans P, Huber W, Strutt D & Zeidler MP (2013) Control of tissue morphology by Fasciclin III-mediated intercellular adhesion. Development, 140(18), 3858-3868.  

  • Bovens SM, Foin N, O'Clery N, Van Der Heiden K, Cuhlmann S, Carlsen H, Barahona M, Evans PC & Krams R (2013) Shear stress and nitric oxide transport affect NFkB dynamics in endothelial cells. European Heart Journal, 34(suppl 1), P582-P582.  

  • Evans PC & Kwak BR (2013) Biomechanical factors in cardiovascular disease.. Cardiovasc Res, 99(2), 229-231.  

  • Van der Heiden K, Gijsen FJH, Narracott A, Hsiao S, Halliday I, Gunn J, Wentzel JJ & Evans PC (2013) The effects of stenting on shear stress: relevance to endothelial injury and repair.. Cardiovasc Res, 99(2), 269-275.  

  • Luong LA, Fragiadaki M, Smith J, Boyle J, Lutz J, Dean JLE, Harten S, Ashcroft M, Walmsley SR, Haskard DO , Maxwell PH et al (2013) Cezanne regulates inflammatory responses to hypoxia in endothelial cells by targeting TRAF6 for deubiquitination.. Circ Res, 112(12), 1583-1591.  

  • Gray C, Bratt D, Lees J, daCosta M, Plant K, Watson OJ, Solaymani-Kohal S, Tazzyman S, Serbanovic-Canic J, Crossman DC , Keavney BD et al (2013) Loss of function of parathyroid hormone receptor 1 induces Notch-dependent aortic defects during zebrafish vascular development.. Arterioscler Thromb Vasc Biol, 33(6), 1257-1263.  

  • Haskard DO, Boyle JJ, Evans PC, Mason JC & Randi AM (2013) Cytoprotective signaling and gene expression in endothelial cells and macrophages-lessons for atherosclerosis.. Microcirculation, 20(3), 203-216.

2012  

  • Warboys CM, de Luca A, Amini N & Evans PC (2012) THE INFLUENCE OF FLOW ON VASCULAR ENDOTHELIAL CELL SENESCENCE. ATHEROSCLEROSIS, 225(2), E6-E6.  

  • Golubnitschaja O & Costigliola V (2012) General Report & Recommendations in Predictive, Preventive and Personalised Medicine 2012: White Paper of the European Association for Predictive, Preventive and Personalised Medicine. EPMA Journal, 3(1).  

  • Dumont O, Mylroie H, Bauer A, Calay D, Sperone A, Thornton C, Hamdulay SS, Ali N, Boyle JJ, Choo JR , Samarel AM et al (2012) Protein kinase Cε activity induces anti-inflammatory and anti-apoptotic genes via an ERK1/2- and NF-κB-dependent pathway to enhance vascular protection.. Biochem J, 447(2), 193-204.  

  • Boyle JJ, Christou I, Iqbal MB, Nguyen AT, Leung VWY, Evans PC, Liu Y, Johns M, Kirkham P & Haskard DO (2012) Solid-phase immunoglobulins IgG and IgM activate macrophages with solid-phase IgM acting via a novel scavenger receptor a pathway.. Am J Pathol, 181(1), 347-361.  

  • Kuhlmann MT, Cuhlmann S, Hoppe I, Krams R, Evans PC, Strijkers GJ, Nicolay K, Hermann S & Schäfers M (2012) Implantation of a carotid cuff for triggering shear-stress induced atherosclerosis in mice.. Journal of visualized experiments : JoVE(59).  

  • Van Der Heiden K, Groen HC, Evans PC, Speelman L, Gijsen F, De Jong M, Van Der Steen AFW & Wentzel JJ (2012) Non-invasive molecular imaging of shear stress-induced endothelial activation and atherosclerotic plaque vulnerability. ASME 2012 Summer Bioengineering Conference, SBC 2012, 91-92.  

  • De Luca A, Warboys CM, Amini N, Ferreira P, Gatehouse P, Firmin D, Mason J, Sherwin S & Evans PC (2012) Image-based computational hemodynamics and microarray analysis of the porcine aortic arch reveals a correlation between shear stress and endothelial cell apoptosis. ASME 2012 Summer Bioengineering Conference, SBC 2012, 923-924.  

  • Pfenniger A, Wong C, Sutter E, Cuhlmann S, Dunoyer-Geindre S, Mach F, Horrevoets AJ, Evans PC, Krams R & Kwak BR (2012) Shear stress modulates the expression of the atheroprotective protein Cx37 in endothelial cells. Journal of Molecular and Cellular Cardiology, 53(2), 299-309.  

  • Kuhlmann MT, Cuhlmann S, Hoppe I, Krams R, Evans PC, Strijkers GJ, Nicolay K, Hermann S & Schäfers M (2012) Implantation of a carotid cuff for triggering shear-stress induced atherosclerosis in mice. Journal of Visualized Experiments(59), 1-6.

 

2011 

  • Gsell W, Cuhlmann S, Van der Heiden K, Tremoleda JL, Khalil M, Clark J, Bird J, Jones H, Krams R & Evans PC (2011) (18)FEDAA is a more specific probe than (18)FDG for imaging vascular inflammation. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 38, S210-S210.  

  • Boyle JJ, Johns M, Lo J, Chiodini A, Ambrose N, Evans PC, Mason JC & Haskard DO (2011) Heme induces heme oxygenase 1 via Nrf2: role in the homeostatic macrophage response to intraplaque hemorrhage.. Arterioscler Thromb Vasc Biol, 31(11), 2685-2691.  

  • Jevon M, Ansari TI, Finch J, Zakkar M, Evans PC, Shurey S, Sibbons PD, Hornick P, Haskard DO & Dorling A (2011) Smooth muscle cells in porcine vein graft intimal hyperplasia are derived from the local vessel wall.. Cardiovasc Pathol, 20(3), e91-e94.  

  • Harling L, Warren OJ, Martin A, Kemp PR, Evans PC, Darzi A & Athanasiou T (2011) Do miniaturized extracorporeal circuits confer significant clinical benefit without compromising safety? A meta-analysis of randomized controlled trials.. ASAIO J, 57(3), 141-151.  

  • Cuhlmann S, Van der Heiden K, Saliba D, Tremoleda JL, Khalil M, Zakkar M, Chaudhury H, Luong LA, Mason JC, Udalova I , Gsell W et al (2011) Disturbed blood flow induces RelA expression via c-Jun N-terminal kinase 1: a novel mode of NF-κB regulation that promotes arterial inflammation.. Circ Res, 108(8), 950-959.  

  • Warboys CM, Amini N, de Luca A & Evans PC (2011) The role of blood flow in determining the sites of atherosclerotic plaques.. F1000 Med Rep, 3. View this article in WRRO  

  • Zakkar M, Luong LA, Chaudhury H, Ruud O, Punjabi PP, Anderson JR, Mullholand JW, Clements AT, Krams R, Foin N , Athanasiou T et al (2011) Dexamethasone arterializes venous endothelial cells by inducing mitogen-activated protein kinase phosphatase-1: a novel antiinflammatory treatment for vein grafts?. Circulation, 123(5), 524-532.  

  • Warboys CM, Amini N, Luca AD & Evans PC (2011) When stress is good. Scientist, 25(2), 52.  

  • Sperone A, Dryden NH, Birdsey GM, Madden L, Johns M, Evans PC, Mason JC, Haskard DO, Boyle JJ, Paleolog EM & Randi AM (2011) The transcription factor Erg inhibits vascular inflammation by repressing NF-kappaB activation and proinflammatory gene expression in endothelial cells.. Arterioscler Thromb Vasc Biol, 31(1), 142-150.  

  • Luong LA & Evans PC (2011) Targeting inhibitor of apoptosis proteins to block vascular inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology, 31(10), 2165-2166.  

  • Evans PC (2011) The influence of sulforaphane on vascular health and its relevance to nutritional approaches to prevent cardiovascular disease. EPMA Journal, 2(1), 9-14.  

  • Halliday I, Atherton M, Care CM, Collins MW, Evans D, Evans PC, Hose DR, Khir AW, König CS, Krams R , Lawford PV et al (2011) Multi-scale interaction of particulate flow and the artery wall. Medical Engineering and Physics, 33(7), 840-848.  

  • Halliday I, Atherton M, Care CM, Collins MW, Evans D, Evans PC, Hose DR, Khir AW, König CS, Krams R , Lawford PV et al (2011) Multi-scale interaction of particulate flow and the artery wall.. Med Eng Phys, 33(7), 840-848.

 

2010  

  • Cuhlmann S, van der Heiden K, Zakkar M, Chaudhury H, Luong LA, Mason J, Haskard DO, Carlsen H, Krams R & Evans PC (2010) YIA4 C Jun N-terminal kinase promotes endothelial activation at atherosclerosis-susceptible sites by enhancing expression of NF- B transcription factors. Heart, 96(17), e10-e10.  

  • Van der Heiden K, Cuhlmann S, Luong LA, Zakkar M & Evans PC (2010) Role of nuclear factor kappaB in cardiovascular health and disease.. Clin Sci (Lond), 118(10), 593-605.  

  • Hamdulay SS, Wang B, Birdsey GM, Ali F, Dumont O, Evans PC, Haskard DO, Wheeler-Jones CP & Mason JC (2010) Celecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endothelium.. Free Radic Biol Med, 48(8), 1013-1023.  

  • Chaudhury H, Zakkar M, Boyle J, Cuhlmann S, van der Heiden K, Luong LA, Davis J, Platt A, Mason JC, Krams R , Haskard DO et al (2010) c-Jun N-terminal kinase primes endothelial cells at atheroprone sites for apoptosis.. Arterioscler Thromb Vasc Biol, 30(3), 546-553.  

  • Amirak E, Zakkar M, Evans PC & Kemp PR (2010) Perfusion of veins at arterial pressure increases the expression of KLF5 and cell cycle genes in smooth muscle cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 391(1), 818-823.  

  • Amirak E, Zakkar M, Evans PC & Kemp PR (2010) Perfusion of veins at arterial pressure increases the expression of KLF5 and cell cycle genes in smooth muscle cells.. Biochem Biophys Res Commun, 391(1), 818-823.  

  • Vossenkämper A, Marchès O, Fairclough PD, Warnes G, Stagg AJ, Lindsay JO, Evans PC, Le Luong A, Croft NM, Naik S , Frankel G et al (2010) Inhibition of NF-κB signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. Journal of Immunology, 185(7), 4118-4127.

 

2009  

  • Zakkar M, Van der Heiden K, Luong LA, Chaudhury H, Cuhlmann S, Hamdulay SS, Krams R, Edirisinghe I, Rahman I, Carlsen H , Haskard DO et al (2009) Activation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state.. Arterioscler Thromb Vasc Biol, 29(11), 1851-1857.  

  • Ali F, Zakkar M, Karu K, Lidington EA, Hamdulay SS, Boyle JJ, Zloh M, Bauer A, Haskard DO, Evans PC & Mason JC (2009) Induction of the cytoprotective enzyme heme oxygenase-1 by statins is enhanced in vascular endothelium exposed to laminar shear stress and impaired by disturbed flow.. J Biol Chem, 284(28), 18882-18892.  

  • Evans PC (2009) Nur77: Orphaned at birth but adopted by the nuclear factor κb signaling pathway. Circulation Research, 104(6), 707-709. 

 

2008 

  • Evans PC (2008) Effects of shear stress on endothelial activation and vascular inflammation. Biomedicine & Pharmacotherapy, 62(8), 503-504.  

  • Ridger V, Krams R, Carpi A & Evans PC (2008) Hemodynamic parameters regulating vascular inflammation and atherosclerosis: a brief update.. Biomed Pharmacother, 62(8), 536-540.  

  • Zakkar M, Chaudhury H, Sandvik G, Enesa K, Luong LA, Cuhlmann S, Mason JC, Krams R, Clark AR, Haskard DO & Evans PC (2008) Increased endothelial mitogen-activated protein kinase phosphatase-1 expression suppresses proinflammatory activation at sites that are resistant to atherosclerosis.. Circ Res, 103(7), 726-732.  

  • Zakkar M, Chaudhury H, Krams R, Mason JC, Clark AR, Haskard DO & Evans PC (2008) MAP KINASE PHOSPHATASE-1 SUPPRESSES ENDOTHELIAL ACTIVATION IN REGIONS OF THE ARTERIAL TREE THAT ARE RESISTANT TO ATHEROSCLEROSIS. Atherosclerosis, 199(2), 465-465.  

  • Birks EJ, Latif N, Enesa K, Folkvang T, Luong LA, Sarathchandra P, Khan M, Ovaa H, Terracciano CM, Barton PJR , Yacoub MH et al (2008) Elevated p53 expression is associated with dysregulation of the ubiquitin-proteasome system in dilated cardiomyopathy.. Cardiovasc Res, 79(3), 472-480.  

  • Enesa K, Ito K, Luong LA, Thorbjornsen I, Phua C, To Y, Dean J, Haskard DO, Boyle J, Adcock I & Evans PC (2008) Hydrogen peroxide prolongs nuclear localization of NF-kappaB in activated cells by suppressing negative regulatory mechanisms.. J Biol Chem, 283(27), 18582-18590.  

  • Kinderlerer AR, Ali F, Johns M, Lidington EA, Leung V, Boyle JJ, Hamdulay SS, Evans PC, Haskard DO & Mason JC (2008) KLF2-dependent, shear stress-induced expression of CD59: a novel cytoprotective mechanism against complement-mediated injury in the vasculature.. J Biol Chem, 283(21), 14636-14644.  

  • Enesa K, Zakkar M, Chaudhury H, Luong LA, Rawlinson L, Mason JC, Haskard DO, Dean JLE & Evans PC (2008) NF-kappaB suppression by the deubiquitinating enzyme Cezanne: a novel negative feedback loop in pro-inflammatory signaling.. J Biol Chem, 283(11), 7036-7045.  

  • Evans P, Slingsby C & Wallace BA (2008) Association of partially folded lens βB2-crystallins with the α-crystallin molecular chaperone. Biochemical Journal, 409(3), 691-699.  

  • Foin N, Evans P & Krams R (2008) Atherosclerosis: cell biology and lipoproteins – new developments in imaging of inflammation of the vulnerable plaque. Current Opinion in Lipidology, 19(1), 98-100.  

  • Lutz J, Luong LA, Strobl M, Deng M, Huang H, Anton M, Zakkar M, Enesa K, Chaudhury H, Haskard DO , Baumann M et al (2008) The A20 gene protects kidneys from ischaemia/reperfusion injury by suppressing pro-inflammatory activation. Journal of Molecular Medicine, 86(12), 1329-1339.

 

2007  

  • Partridge J, Carlsen H, Enesa K, Chaudhury H, Zakkar M, Luong L, Kinderlerer A, Johns M, Blomhoff R, Mason JC , Haskard DO et al (2007) Laminar shear stress acts as a switch to regulate divergent functions of NF-kappaB in endothelial cells.. FASEB J, 21(13), 3553-3561.  

  • Evans P, Bateman OA, Slingsby C & Wallace BA (2007) A reference dataset for circular dichroism spectroscopy tailored for the βγ-crystallin lens proteins. Experimental Eye Research, 84(5), 1001-1008.  

  • Adcock I & Evans PC (2007) Resolution of Inflammatory Responses: a brief introduction.. Biochem Soc Trans, 35(Pt 2), 261-262.  

  • Enesa K & Evans PC (2007) Ubiquitin in pro-inflammatory signalling: Chains of command. Biochemist, 29(4), 24-27.  

  • Helderman F, Segers D, De Crom R, Hierck BP, Poelmann RE, Evans PC & Krams R (2007) Effect of shear stress on vascular inflammation and plaque development. Current Opinion in Lipidology, 18(5), 527-533.